public/data/source_tsvs/ClearityFoundation_INTERACTIONS.tsv
gene_name entrez_gene_id reported_drug_response reported_gene_name drug_name drug_trade_name pubchem_id drug_class drug_subclass linked_class_info interaction_type
AKT1 207 Sensitivity AKT MUT/AMP ARQ092 AKT Inhibitors Clinical Trial Agents (For Ovarian and other Cancers) https://www.clearityfoundation.org/healthcare-pros/drugs-bio/clinicla-trial-agents-ovarian/pi3k-inhibitors.aspx Biomarker
AKT1 207 Sensitivity AKT MUT/AMP MK2206 46930998 AKT Inhibitors Clinical Trial Agents (For Ovarian and other Cancers) https://www.clearityfoundation.org/healthcare-pros/drugs-bio/clinicla-trial-agents-ovarian/pi3k-inhibitors.aspx Biomarker
AKT1 207 Sensitivity AKT MUT/AMP Triciribine 65399 AKT Inhibitors Clinical Trial Agents (For Ovarian and other Cancers) https://www.clearityfoundation.org/healthcare-pros/drugs-bio/clinicla-trial-agents-ovarian/pi3k-inhibitors.aspx Biomarker
ATM 427 Sensitivity ATM MUT BMN673 44819242 PARP Inhibitors Clinical Trial Agents (For Ovarian and other Cancers) https://www.clearityfoundation.org/healthcare-pros/drugs-bio/clinicla-trial-agents-ovarian/parp-inhibitors.aspx Biomarker
ATM 427 Sensitivity ATM MUT E7449 PARP Inhibitors Clinical Trial Agents (For Ovarian and other Cancers) https://www.clearityfoundation.org/healthcare-pros/drugs-bio/clinicla-trial-agents-ovarian/parp-inhibitors.aspx Biomarker
ATM 427 Sensitivity ATM MUT Niraparib 24958200 PARP Inhibitors Clinical Trial Agents (For Ovarian and other Cancers) https://www.clearityfoundation.org/healthcare-pros/drugs-bio/clinicla-trial-agents-ovarian/parp-inhibitors.aspx Biomarker
ATM 427 Sensitivity ATM MUT Olaparib 23725625 PARP Inhibitors Clinical Trial Agents (For Ovarian and other Cancers) https://www.clearityfoundation.org/healthcare-pros/drugs-bio/clinicla-trial-agents-ovarian/parp-inhibitors.aspx Biomarker
ATM 427 Sensitivity ATM MUT Rucaparib 9931954 PARP Inhibitors Clinical Trial Agents (For Ovarian and other Cancers) https://www.clearityfoundation.org/healthcare-pros/drugs-bio/clinicla-trial-agents-ovarian/parp-inhibitors.aspx Biomarker
ATM 427 Sensitivity ATM MUT Veliparib 11960529 PARP Inhibitors Clinical Trial Agents (For Ovarian and other Cancers) https://www.clearityfoundation.org/healthcare-pros/drugs-bio/clinicla-trial-agents-ovarian/parp-inhibitors.aspx Biomarker
ATR 545 Sensitivity ATR MUT BMN673 44819242 PARP Inhibitors Clinical Trial Agents (For Ovarian and other Cancers) https://www.clearityfoundation.org/healthcare-pros/drugs-bio/clinicla-trial-agents-ovarian/parp-inhibitors.aspx Biomarker
ATR 545 Sensitivity ATR MUT E7449 PARP Inhibitors Clinical Trial Agents (For Ovarian and other Cancers) https://www.clearityfoundation.org/healthcare-pros/drugs-bio/clinicla-trial-agents-ovarian/parp-inhibitors.aspx Biomarker
ATR 545 Sensitivity ATR MUT Niraparib 24958200 PARP Inhibitors Clinical Trial Agents (For Ovarian and other Cancers) https://www.clearityfoundation.org/healthcare-pros/drugs-bio/clinicla-trial-agents-ovarian/parp-inhibitors.aspx Biomarker
ATR 545 Sensitivity ATR MUT Olaparib 23725625 PARP Inhibitors Clinical Trial Agents (For Ovarian and other Cancers) https://www.clearityfoundation.org/healthcare-pros/drugs-bio/clinicla-trial-agents-ovarian/parp-inhibitors.aspx Biomarker
ATR 545 Sensitivity ATR MUT Rucaparib 9931954 PARP Inhibitors Clinical Trial Agents (For Ovarian and other Cancers) https://www.clearityfoundation.org/healthcare-pros/drugs-bio/clinicla-trial-agents-ovarian/parp-inhibitors.aspx Biomarker
ATR 545 Sensitivity ATR MUT Veliparib 11960529 PARP Inhibitors Clinical Trial Agents (For Ovarian and other Cancers) https://www.clearityfoundation.org/healthcare-pros/drugs-bio/clinicla-trial-agents-ovarian/parp-inhibitors.aspx Biomarker
BCL2 596 Resistance Bcl-2 Carboplatin Paraplatin 10339178 Platinum Cytotoxic Drugs https://www.clearityfoundation.org/healthcare-pros/drugs-bio/cytotoxic-drugs/platinum-drugs.aspx Biomarker
BCL2 596 Resistance Bcl-2 Cisplatin Platinol 84093 Platinum Cytotoxic Drugs https://www.clearityfoundation.org/healthcare-pros/drugs-bio/cytotoxic-drugs/platinum-drugs.aspx Biomarker
BCL2 596 Resistance Bcl-2 Oxaliplatin Eloxatin 5310940 Platinum Cytotoxic Drugs https://www.clearityfoundation.org/healthcare-pros/drugs-bio/cytotoxic-drugs/platinum-drugs.aspx Biomarker
BIRC5 332 Resistance Survivin Docetaxel Taxotere 148124 Taxanes Cytotoxic Drugs https://www.clearityfoundation.org/healthcare-pros/drugs-bio/cytotoxic-drugs/taxanes.aspx Biomarker
BIRC5 332 Resistance Survivin Paclitaxel Taxol 36314 Taxanes Cytotoxic Drugs https://www.clearityfoundation.org/healthcare-pros/drugs-bio/cytotoxic-drugs/taxanes.aspx Biomarker
BRAF 673 Sensitivity BRAF MUT Vemurafenib Zelboraf 42611257 B-RAF Inhibitors Clinical Trial Agents (Approved in other Cancers) https://www.clearityfoundation.org/healthcare-pros/drugs-bio/clinicla-trial-agents/braf-inhibitors.aspx Biomarker
BRAF 673 Sensitivity BRAF MUT/AMP GDC-0973 16222096 MEK Inhibitors Clinical Trial Agents (For Ovarian and other Cancers) https://www.clearityfoundation.org/healthcare-pros/drugs-bio/clinicla-trial-agents-ovarian/mek-inhibitors.aspx Biomarker
BRAF 673 Sensitivity BRAF MUT/AMP MEK162 10288191 MEK Inhibitors Clinical Trial Agents (For Ovarian and other Cancers) https://www.clearityfoundation.org/healthcare-pros/drugs-bio/clinicla-trial-agents-ovarian/mek-inhibitors.aspx Biomarker
BRAF 673 Sensitivity BRAF MUT/AMP PD-325901 9826528 MEK Inhibitors Clinical Trial Agents (For Ovarian and other Cancers) https://www.clearityfoundation.org/healthcare-pros/drugs-bio/clinicla-trial-agents-ovarian/mek-inhibitors.aspx Biomarker
BRAF 673 Sensitivity BRAF MUT/AMP Pimasertib 44187362 MEK Inhibitors Clinical Trial Agents (For Ovarian and other Cancers) https://www.clearityfoundation.org/healthcare-pros/drugs-bio/clinicla-trial-agents-ovarian/mek-inhibitors.aspx Biomarker
BRAF 673 Sensitivity BRAF MUT/AMP Rafametinib MEK Inhibitors Clinical Trial Agents (For Ovarian and other Cancers) https://www.clearityfoundation.org/healthcare-pros/drugs-bio/clinicla-trial-agents-ovarian/mek-inhibitors.aspx Biomarker
BRAF 673 Sensitivity BRAF MUT/AMP Selumetinib 10127622 MEK Inhibitors Clinical Trial Agents (For Ovarian and other Cancers) https://www.clearityfoundation.org/healthcare-pros/drugs-bio/clinicla-trial-agents-ovarian/mek-inhibitors.aspx Biomarker
BRAF 673 Sensitivity BRAF MUT/AMP Trametinib 11707110 MEK Inhibitors Clinical Trial Agents (For Ovarian and other Cancers) https://www.clearityfoundation.org/healthcare-pros/drugs-bio/clinicla-trial-agents-ovarian/mek-inhibitors.aspx Biomarker
BRCA1 672 Sensitivity BRCA1 MUT BMN673 44819242 PARP Inhibitors Clinical Trial Agents (For Ovarian and other Cancers) https://www.clearityfoundation.org/healthcare-pros/drugs-bio/clinicla-trial-agents-ovarian/parp-inhibitors.aspx Biomarker
BRCA1 672 Sensitivity BRCA1 MUT E7449 PARP Inhibitors Clinical Trial Agents (For Ovarian and other Cancers) https://www.clearityfoundation.org/healthcare-pros/drugs-bio/clinicla-trial-agents-ovarian/parp-inhibitors.aspx Biomarker
BRCA1 672 Sensitivity BRCA1 MUT Niraparib 24958200 PARP Inhibitors Clinical Trial Agents (For Ovarian and other Cancers) https://www.clearityfoundation.org/healthcare-pros/drugs-bio/clinicla-trial-agents-ovarian/parp-inhibitors.aspx Biomarker
BRCA1 672 Sensitivity BRCA1 MUT Olaparib 23725625 PARP Inhibitors Clinical Trial Agents (For Ovarian and other Cancers) https://www.clearityfoundation.org/healthcare-pros/drugs-bio/clinicla-trial-agents-ovarian/parp-inhibitors.aspx Biomarker
BRCA1 672 Sensitivity BRCA1 MUT Rucaparib 9931954 PARP Inhibitors Clinical Trial Agents (For Ovarian and other Cancers) https://www.clearityfoundation.org/healthcare-pros/drugs-bio/clinicla-trial-agents-ovarian/parp-inhibitors.aspx Biomarker
BRCA1 672 Sensitivity BRCA1 MUT Veliparib 11960529 PARP Inhibitors Clinical Trial Agents (For Ovarian and other Cancers) https://www.clearityfoundation.org/healthcare-pros/drugs-bio/clinicla-trial-agents-ovarian/parp-inhibitors.aspx Biomarker
BRCA1 672 Sensitivity BRCA1 MUT Carboplatin Paraplatin 10339178 Platinum Cytotoxic Drugs https://www.clearityfoundation.org/healthcare-pros/drugs-bio/cytotoxic-drugs/platinum-drugs.aspx Biomarker
BRCA1 672 Sensitivity BRCA1 MUT Cisplatin Platinol 84093 Platinum Cytotoxic Drugs https://www.clearityfoundation.org/healthcare-pros/drugs-bio/cytotoxic-drugs/platinum-drugs.aspx Biomarker
BRCA1 672 Sensitivity BRCA1 MUT Oxaliplatin Eloxatin 5310940 Platinum Cytotoxic Drugs https://www.clearityfoundation.org/healthcare-pros/drugs-bio/cytotoxic-drugs/platinum-drugs.aspx Biomarker
BRCA2 675 Sensitivity BRCA2 MUT BMN673 44819242 PARP Inhibitors Clinical Trial Agents (For Ovarian and other Cancers) https://www.clearityfoundation.org/healthcare-pros/drugs-bio/clinicla-trial-agents-ovarian/parp-inhibitors.aspx Biomarker
BRCA2 675 Sensitivity BRCA2 MUT E7449 PARP Inhibitors Clinical Trial Agents (For Ovarian and other Cancers) https://www.clearityfoundation.org/healthcare-pros/drugs-bio/clinicla-trial-agents-ovarian/parp-inhibitors.aspx Biomarker
BRCA2 675 Sensitivity BRCA2 MUT Niraparib 24958200 PARP Inhibitors Clinical Trial Agents (For Ovarian and other Cancers) https://www.clearityfoundation.org/healthcare-pros/drugs-bio/clinicla-trial-agents-ovarian/parp-inhibitors.aspx Biomarker
BRCA2 675 Sensitivity BRCA2 MUT Olaparib 23725625 PARP Inhibitors Clinical Trial Agents (For Ovarian and other Cancers) https://www.clearityfoundation.org/healthcare-pros/drugs-bio/clinicla-trial-agents-ovarian/parp-inhibitors.aspx Biomarker
BRCA2 675 Sensitivity BRCA2 MUT Rucaparib 9931954 PARP Inhibitors Clinical Trial Agents (For Ovarian and other Cancers) https://www.clearityfoundation.org/healthcare-pros/drugs-bio/clinicla-trial-agents-ovarian/parp-inhibitors.aspx Biomarker
BRCA2 675 Sensitivity BRCA2 MUT Veliparib 11960529 PARP Inhibitors Clinical Trial Agents (For Ovarian and other Cancers) https://www.clearityfoundation.org/healthcare-pros/drugs-bio/clinicla-trial-agents-ovarian/parp-inhibitors.aspx Biomarker
CCND1 595 Sensitivity CCND1 AMP BAY1000394 CDK4 Inhibitors Clinical Trial Agents (For Ovarian and other Cancers) https://www.clearityfoundation.org/healthcare-pros/drugs-bio/clinicla-trial-agents-ovarian/cdk4-inhibitors.aspx Biomarker
CCND1 595 Sensitivity CCND1 AMP LEE011 CDK4 Inhibitors Clinical Trial Agents (For Ovarian and other Cancers) https://www.clearityfoundation.org/healthcare-pros/drugs-bio/clinicla-trial-agents-ovarian/cdk4-inhibitors.aspx Biomarker
CCND1 595 Sensitivity CCND1 AMP LY2835219 71576678 CDK4 Inhibitors Clinical Trial Agents (For Ovarian and other Cancers) https://www.clearityfoundation.org/healthcare-pros/drugs-bio/clinicla-trial-agents-ovarian/cdk4-inhibitors.aspx Biomarker
CCND1 595 Sensitivity CCND1 AMP PD 0332991 5330286 CDK4 Inhibitors Clinical Trial Agents (For Ovarian and other Cancers) https://www.clearityfoundation.org/healthcare-pros/drugs-bio/clinicla-trial-agents-ovarian/cdk4-inhibitors.aspx Biomarker
CCND2 894 Sensitivity CCND2 AMP BAY1000394 CDK4 Inhibitors Clinical Trial Agents (For Ovarian and other Cancers) https://www.clearityfoundation.org/healthcare-pros/drugs-bio/clinicla-trial-agents-ovarian/cdk4-inhibitors.aspx Biomarker
CCND2 894 Sensitivity CCND2 AMP LEE011 CDK4 Inhibitors Clinical Trial Agents (For Ovarian and other Cancers) https://www.clearityfoundation.org/healthcare-pros/drugs-bio/clinicla-trial-agents-ovarian/cdk4-inhibitors.aspx Biomarker
CCND2 894 Sensitivity CCND2 AMP LY2835219 71576678 CDK4 Inhibitors Clinical Trial Agents (For Ovarian and other Cancers) https://www.clearityfoundation.org/healthcare-pros/drugs-bio/clinicla-trial-agents-ovarian/cdk4-inhibitors.aspx Biomarker
CCND2 894 Sensitivity CCND2 AMP PD 0332991 5330286 CDK4 Inhibitors Clinical Trial Agents (For Ovarian and other Cancers) https://www.clearityfoundation.org/healthcare-pros/drugs-bio/clinicla-trial-agents-ovarian/cdk4-inhibitors.aspx Biomarker
CCND3 896 Sensitivity CCND3 AMP BAY1000394 CDK4 Inhibitors Clinical Trial Agents (For Ovarian and other Cancers) https://www.clearityfoundation.org/healthcare-pros/drugs-bio/clinicla-trial-agents-ovarian/cdk4-inhibitors.aspx Biomarker
CCND3 896 Sensitivity CCND3 AMP LEE011 CDK4 Inhibitors Clinical Trial Agents (For Ovarian and other Cancers) https://www.clearityfoundation.org/healthcare-pros/drugs-bio/clinicla-trial-agents-ovarian/cdk4-inhibitors.aspx Biomarker
CCND3 896 Sensitivity CCND3 AMP LY2835219 71576678 CDK4 Inhibitors Clinical Trial Agents (For Ovarian and other Cancers) https://www.clearityfoundation.org/healthcare-pros/drugs-bio/clinicla-trial-agents-ovarian/cdk4-inhibitors.aspx Biomarker
CCND3 896 Sensitivity CCND3 AMP PD 0332991 5330286 CDK4 Inhibitors Clinical Trial Agents (For Ovarian and other Cancers) https://www.clearityfoundation.org/healthcare-pros/drugs-bio/clinicla-trial-agents-ovarian/cdk4-inhibitors.aspx Biomarker
CCNE1 898 Sensitivity CCNE1 AMP Alisertib 24771867 AURKA Inhibitors Clinical Trial Agents (For Ovarian and other Cancers) https://www.clearityfoundation.org/healthcare-pros/drugs-bio/clinicla-trial-agents-ovarian/cdk2-aurka-inhibitors.aspx Biomarker
CCNE1 898 Sensitivity CCNE1 AMP AMG900 24856041 AURKA Inhibitors Clinical Trial Agents (For Ovarian and other Cancers) https://www.clearityfoundation.org/healthcare-pros/drugs-bio/clinicla-trial-agents-ovarian/cdk2-aurka-inhibitors.aspx Biomarker
CCNE1 898 Sensitivity CCNE1 AMP BAY1000394 CDK2 Inhibitors Clinical Trial Agents (For Ovarian and other Cancers) https://www.clearityfoundation.org/healthcare-pros/drugs-bio/clinicla-trial-agents-ovarian/cdk2-aurka-inhibitors.aspx Biomarker
CCNE1 898 Sensitivity CCNE1 AMP Dinaciclib 46926350 CDK2 Inhibitors Clinical Trial Agents (For Ovarian and other Cancers) https://www.clearityfoundation.org/healthcare-pros/drugs-bio/clinicla-trial-agents-ovarian/cdk2-aurka-inhibitors.aspx Biomarker
CDK4 1019 Sensitivity CDK AMP BAY1000394 CDK4 Inhibitors Clinical Trial Agents (For Ovarian and other Cancers) https://www.clearityfoundation.org/healthcare-pros/drugs-bio/clinicla-trial-agents-ovarian/cdk4-inhibitors.aspx Biomarker
CDK4 1019 Sensitivity CDK AMP LEE011 CDK4 Inhibitors Clinical Trial Agents (For Ovarian and other Cancers) https://www.clearityfoundation.org/healthcare-pros/drugs-bio/clinicla-trial-agents-ovarian/cdk4-inhibitors.aspx Biomarker
CDK4 1019 Sensitivity CDK AMP LY2835219 71576678 CDK4 Inhibitors Clinical Trial Agents (For Ovarian and other Cancers) https://www.clearityfoundation.org/healthcare-pros/drugs-bio/clinicla-trial-agents-ovarian/cdk4-inhibitors.aspx Biomarker
CDK4 1019 Sensitivity CDK AMP PD 0332991 5330286 CDK4 Inhibitors Clinical Trial Agents (For Ovarian and other Cancers) https://www.clearityfoundation.org/healthcare-pros/drugs-bio/clinicla-trial-agents-ovarian/cdk4-inhibitors.aspx Biomarker
CDKN2A 1029 Sensitivity CDKN2A (p16) MUT/DEL BAY1000394 CDK4 Inhibitors Clinical Trial Agents (For Ovarian and other Cancers) https://www.clearityfoundation.org/healthcare-pros/drugs-bio/clinicla-trial-agents-ovarian/cdk4-inhibitors.aspx Biomarker
CDKN2A 1029 Sensitivity CDKN2A (p16) MUT/DEL LEE011 CDK4 Inhibitors Clinical Trial Agents (For Ovarian and other Cancers) https://www.clearityfoundation.org/healthcare-pros/drugs-bio/clinicla-trial-agents-ovarian/cdk4-inhibitors.aspx Biomarker
CDKN2A 1029 Sensitivity CDKN2A (p16) MUT/DEL LY2835219 71576678 CDK4 Inhibitors Clinical Trial Agents (For Ovarian and other Cancers) https://www.clearityfoundation.org/healthcare-pros/drugs-bio/clinicla-trial-agents-ovarian/cdk4-inhibitors.aspx Biomarker
CDKN2A 1029 Sensitivity CDKN2A (p16) MUT/DEL PD 0332991 5330286 CDK4 Inhibitors Clinical Trial Agents (For Ovarian and other Cancers) https://www.clearityfoundation.org/healthcare-pros/drugs-bio/clinicla-trial-agents-ovarian/cdk4-inhibitors.aspx Biomarker
EGFR 1956 Sensitivity EGFR MUT, AMP Cetuximab Erbitux 56842117 EGFR Inhibitors Clinical Trial Agents (Approved in other Cancers) https://www.clearityfoundation.org/healthcare-pros/drugs-bio/clinicla-trial-agents/egfr-inhibitors.aspx Biomarker
EGFR 1956 Sensitivity EGFR MUT, AMP Erlotinib Tarceva 176870 EGFR Inhibitors Clinical Trial Agents (Approved in other Cancers) https://www.clearityfoundation.org/healthcare-pros/drugs-bio/clinicla-trial-agents/egfr-inhibitors.aspx Biomarker
EGFR 1956 Sensitivity EGFR MUT, AMP Gefitinib Iressa 123631 EGFR Inhibitors Clinical Trial Agents (Approved in other Cancers) https://www.clearityfoundation.org/healthcare-pros/drugs-bio/clinicla-trial-agents/egfr-inhibitors.aspx Biomarker
EGFR 1956 Sensitivity EGFR MUT, AMP Panitumumab Vectibix EGFR Inhibitors Clinical Trial Agents (Approved in other Cancers) https://www.clearityfoundation.org/healthcare-pros/drugs-bio/clinicla-trial-agents/egfr-inhibitors.aspx Biomarker
EGFR 1956 Sensitivity EGFR MUT, AMP Vandetanib Capreisa 3081361 EGFR Inhibitors Clinical Trial Agents (Approved in other Cancers) https://www.clearityfoundation.org/healthcare-pros/drugs-bio/clinicla-trial-agents/egfr-inhibitors.aspx Biomarker
ERBB2 2064 Sensitivity HER2 AMP Lapatinib Tykerb 208908 HER2 Inhibitors Clinical Trial Agents (Approved in other Cancers) https://www.clearityfoundation.org/healthcare-pros/drugs-bio/clinicla-trial-agents/her2-inhibitors.aspx Biomarker
ERBB2 2064 Sensitivity HER2 AMP Pertuzumab Perjeta HER2 Inhibitors Clinical Trial Agents (Approved in other Cancers) https://www.clearityfoundation.org/healthcare-pros/drugs-bio/clinicla-trial-agents/her2-inhibitors.aspx Biomarker
ERBB2 2064 Sensitivity HER2 AMP Trastuzumab Herceptin 9903 HER2 Inhibitors Clinical Trial Agents (Approved in other Cancers) https://www.clearityfoundation.org/healthcare-pros/drugs-bio/clinicla-trial-agents/her2-inhibitors.aspx Biomarker
ESR1 2099 Sensitivity ER Tamoxifen Nolvadex 2733526 Anti-Estrogens Hormonal Therapies https://www.clearityfoundation.org/healthcare-pros/drugs-bio/hormonal-therapies/hormonal-therapy.aspx Biomarker
ESR1 2099 Sensitivity ER Anastrozole Arimidex 2187 Aromatase Inhibitors Hormonal Therapies https://www.clearityfoundation.org/healthcare-pros/drugs-bio/hormonal-therapies/hormonal-therapy.aspx Biomarker
ESR1 2099 Sensitivity ER Letrozole Femara 3902 Aromatase Inhibitors Hormonal Therapies https://www.clearityfoundation.org/healthcare-pros/drugs-bio/hormonal-therapies/hormonal-therapy.aspx Biomarker
KRAS 3845 Resistance KRAS MUT Cetuximab Erbitux 56842117 EGFR Inhibitors Clinical Trial Agents (Approved in other Cancers) https://www.clearityfoundation.org/healthcare-pros/drugs-bio/clinicla-trial-agents/egfr-inhibitors.aspx Biomarker
KRAS 3845 Resistance KRAS MUT Erlotinib Tarceva 176870 EGFR Inhibitors Clinical Trial Agents (Approved in other Cancers) https://www.clearityfoundation.org/healthcare-pros/drugs-bio/clinicla-trial-agents/egfr-inhibitors.aspx Biomarker
KRAS 3845 Resistance KRAS MUT Gefitinib Iressa 123631 EGFR Inhibitors Clinical Trial Agents (Approved in other Cancers) https://www.clearityfoundation.org/healthcare-pros/drugs-bio/clinicla-trial-agents/egfr-inhibitors.aspx Biomarker
KRAS 3845 Resistance KRAS MUT Panitumumab Vectibix EGFR Inhibitors Clinical Trial Agents (Approved in other Cancers) https://www.clearityfoundation.org/healthcare-pros/drugs-bio/clinicla-trial-agents/egfr-inhibitors.aspx Biomarker
KRAS 3845 Resistance KRAS MUT Vandetanib Capreisa 3081361 EGFR Inhibitors Clinical Trial Agents (Approved in other Cancers) https://www.clearityfoundation.org/healthcare-pros/drugs-bio/clinicla-trial-agents/egfr-inhibitors.aspx Biomarker
KRAS 3845 Resistance KRAS MUT Everolimus Afinitor 6442177 mTOR Inhibitors Clinical Trial Agents (Approved in other Cancers) https://www.clearityfoundation.org/healthcare-pros/drugs-bio/clinicla-trial-agents/mtor-inhibitors.aspx Biomarker
KRAS 3845 Resistance KRAS MUT Temsirolimus Torisel 6918289 mTOR Inhibitors Clinical Trial Agents (Approved in other Cancers) https://www.clearityfoundation.org/healthcare-pros/drugs-bio/clinicla-trial-agents/mtor-inhibitors.aspx Biomarker
KRAS 3845 Sensitivity KRAS MUT/AMP GDC-0973 16222096 MEK Inhibitors Clinical Trial Agents (For Ovarian and other Cancers) https://www.clearityfoundation.org/healthcare-pros/drugs-bio/clinicla-trial-agents-ovarian/mek-inhibitors.aspx Biomarker
KRAS 3845 Sensitivity KRAS MUT/AMP MEK162 10288191 MEK Inhibitors Clinical Trial Agents (For Ovarian and other Cancers) https://www.clearityfoundation.org/healthcare-pros/drugs-bio/clinicla-trial-agents-ovarian/mek-inhibitors.aspx Biomarker
KRAS 3845 Sensitivity KRAS MUT/AMP PD-325901 9826528 MEK Inhibitors Clinical Trial Agents (For Ovarian and other Cancers) https://www.clearityfoundation.org/healthcare-pros/drugs-bio/clinicla-trial-agents-ovarian/mek-inhibitors.aspx Biomarker
KRAS 3845 Sensitivity KRAS MUT/AMP Pimasertib 44187362 MEK Inhibitors Clinical Trial Agents (For Ovarian and other Cancers) https://www.clearityfoundation.org/healthcare-pros/drugs-bio/clinicla-trial-agents-ovarian/mek-inhibitors.aspx Biomarker
KRAS 3845 Sensitivity KRAS MUT/AMP Rafametinib MEK Inhibitors Clinical Trial Agents (For Ovarian and other Cancers) https://www.clearityfoundation.org/healthcare-pros/drugs-bio/clinicla-trial-agents-ovarian/mek-inhibitors.aspx Biomarker
KRAS 3845 Sensitivity KRAS MUT/AMP Selumetinib 10127622 MEK Inhibitors Clinical Trial Agents (For Ovarian and other Cancers) https://www.clearityfoundation.org/healthcare-pros/drugs-bio/clinicla-trial-agents-ovarian/mek-inhibitors.aspx Biomarker
KRAS 3845 Sensitivity KRAS MUT/AMP Trametinib 11707110 MEK Inhibitors Clinical Trial Agents (For Ovarian and other Cancers) https://www.clearityfoundation.org/healthcare-pros/drugs-bio/clinicla-trial-agents-ovarian/mek-inhibitors.aspx Biomarker
MET 4233 Sensitivity c-MET AMP Cabozantanib Cometriq 25102847 cMET Inhibitors Clinical Trial Agents (Approved in other Cancers) https://www.clearityfoundation.org/healthcare-pros/drugs-bio/clinicla-trial-agents/cmet-inhibitors.aspx Biomarker
MET 4233 Sensitivity c-MET AMP Crizotinib Xalkori 11626560 cMET Inhibitors Clinical Trial Agents (Approved in other Cancers) https://www.clearityfoundation.org/healthcare-pros/drugs-bio/clinicla-trial-agents/cmet-inhibitors.aspx Biomarker
MGMT 4255 Sensitivity MGMT Temolozomide Temodar 5394 Alkylating Agents Clinical Trial Agents (Approved in other Cancers) Biomarker
MYC 4609 Sensitivity MYC AMP Alisertib 24771867 AURKA Inhibitors Clinical Trial Agents (For Ovarian and other Cancers) https://www.clearityfoundation.org/healthcare-pros/drugs-bio/clinicla-trial-agents-ovarian/cdk2-aurka-inhibitors.aspx Biomarker
MYC 4609 Sensitivity MYC AMP AMG900 24856041 AURKA Inhibitors Clinical Trial Agents (For Ovarian and other Cancers) https://www.clearityfoundation.org/healthcare-pros/drugs-bio/clinicla-trial-agents-ovarian/cdk2-aurka-inhibitors.aspx Biomarker
MYC 4609 Sensitivity MYC AMP BAY1000394 CDK2 Inhibitors Clinical Trial Agents (For Ovarian and other Cancers) https://www.clearityfoundation.org/healthcare-pros/drugs-bio/clinicla-trial-agents-ovarian/cdk2-aurka-inhibitors.aspx Biomarker
MYC 4609 Sensitivity MYC AMP Dinaciclib 46926350 CDK2 Inhibitors Clinical Trial Agents (For Ovarian and other Cancers) https://www.clearityfoundation.org/healthcare-pros/drugs-bio/clinicla-trial-agents-ovarian/cdk2-aurka-inhibitors.aspx Biomarker
NF1 4763 Sensitivity NF1 MUT/DEL GDC-0973 16222096 MEK Inhibitors Clinical Trial Agents (For Ovarian and other Cancers) https://www.clearityfoundation.org/healthcare-pros/drugs-bio/clinicla-trial-agents-ovarian/mek-inhibitors.aspx Biomarker
NF1 4763 Sensitivity NF1 MUT/DEL MEK162 10288191 MEK Inhibitors Clinical Trial Agents (For Ovarian and other Cancers) https://www.clearityfoundation.org/healthcare-pros/drugs-bio/clinicla-trial-agents-ovarian/mek-inhibitors.aspx Biomarker
NF1 4763 Sensitivity NF1 MUT/DEL PD-325901 9826528 MEK Inhibitors Clinical Trial Agents (For Ovarian and other Cancers) https://www.clearityfoundation.org/healthcare-pros/drugs-bio/clinicla-trial-agents-ovarian/mek-inhibitors.aspx Biomarker
NF1 4763 Sensitivity NF1 MUT/DEL Pimasertib 44187362 MEK Inhibitors Clinical Trial Agents (For Ovarian and other Cancers) https://www.clearityfoundation.org/healthcare-pros/drugs-bio/clinicla-trial-agents-ovarian/mek-inhibitors.aspx Biomarker
NF1 4763 Sensitivity NF1 MUT/DEL Rafametinib MEK Inhibitors Clinical Trial Agents (For Ovarian and other Cancers) https://www.clearityfoundation.org/healthcare-pros/drugs-bio/clinicla-trial-agents-ovarian/mek-inhibitors.aspx Biomarker
NF1 4763 Sensitivity NF1 MUT/DEL Selumetinib 10127622 MEK Inhibitors Clinical Trial Agents (For Ovarian and other Cancers) https://www.clearityfoundation.org/healthcare-pros/drugs-bio/clinicla-trial-agents-ovarian/mek-inhibitors.aspx Biomarker
NF1 4763 Sensitivity NF1 MUT/DEL Trametinib 11707110 MEK Inhibitors Clinical Trial Agents (For Ovarian and other Cancers) https://www.clearityfoundation.org/healthcare-pros/drugs-bio/clinicla-trial-agents-ovarian/mek-inhibitors.aspx Biomarker
PGP 283871 Resistance PGP Docetaxel Taxotere 148124 Taxanes Cytotoxic Drugs https://www.clearityfoundation.org/healthcare-pros/drugs-bio/cytotoxic-drugs/taxanes.aspx Biomarker
PGP 283871 Resistance PGP Paclitaxel Taxol 36314 Taxanes Cytotoxic Drugs https://www.clearityfoundation.org/healthcare-pros/drugs-bio/cytotoxic-drugs/taxanes.aspx Biomarker
PGP 283871 Resistance PGP Etoposide Toposar 36462 Topoisomerase 2 Inhibitors Cytotoxic Drugs https://www.clearityfoundation.org/healthcare-pros/drugs-bio/cytotoxic-drugs/topo-ii.aspx Biomarker
PGP 283871 Resistance PGP Etoposide Toposar 36462 Topoisomerase 2 Inhibitors Cytotoxic Drugs https://www.clearityfoundation.org/healthcare-pros/drugs-bio/cytotoxic-drugs/topo-ii.aspx Biomarker
PGR 5241 Sensitivity PR Tamoxifen Nolvadex 2733526 Anti-Estrogens Hormonal Therapies https://www.clearityfoundation.org/healthcare-pros/drugs-bio/hormonal-therapies/hormonal-therapy.aspx Biomarker
PGR 5241 Sensitivity PR Anastrozole Arimidex 2187 Aromatase Inhibitors Hormonal Therapies https://www.clearityfoundation.org/healthcare-pros/drugs-bio/hormonal-therapies/hormonal-therapy.aspx Biomarker
PGR 5241 Sensitivity PR Letrozole Femara 3902 Aromatase Inhibitors Hormonal Therapies https://www.clearityfoundation.org/healthcare-pros/drugs-bio/hormonal-therapies/hormonal-therapy.aspx Biomarker
PGR 5241 Sensitivity PR Megestrol acetate Megace 11683 Progestins Hormonal Therapies https://www.clearityfoundation.org/healthcare-pros/drugs-bio/hormonal-therapies/hormonal-therapy.aspx Biomarker
PIK3CA 5290 Sensitivity PIK3CA MUT Everolimus Afinitor 6442177 mTOR Inhibitors Clinical Trial Agents (Approved in other Cancers) https://www.clearityfoundation.org/healthcare-pros/drugs-bio/clinicla-trial-agents/mtor-inhibitors.aspx Biomarker
PIK3CA 5290 Sensitivity PIK3CA MUT Temsirolimus Torisel 6918289 mTOR Inhibitors Clinical Trial Agents (Approved in other Cancers) https://www.clearityfoundation.org/healthcare-pros/drugs-bio/clinicla-trial-agents/mtor-inhibitors.aspx Biomarker
PIK3CA 5290 Sensitivity PIK3CA MUT/AMP BAY80-6946 24989044 PI3K Inhibitors Clinical Trial Agents (For Ovarian and other Cancers) https://www.clearityfoundation.org/healthcare-pros/drugs-bio/clinicla-trial-agents-ovarian/pi3k-inhibitors.aspx Biomarker
PIK3CA 5290 Sensitivity PIK3CA MUT/AMP BYL719 56649450 PI3K Inhibitors Clinical Trial Agents (For Ovarian and other Cancers) https://www.clearityfoundation.org/healthcare-pros/drugs-bio/clinicla-trial-agents-ovarian/pi3k-inhibitors.aspx Biomarker
PIK3CA 5290 Sensitivity PIK3CA MUT/AMP XL-147 1893730 PI3K Inhibitors Clinical Trial Agents (For Ovarian and other Cancers) https://www.clearityfoundation.org/healthcare-pros/drugs-bio/clinicla-trial-agents-ovarian/pi3k-inhibitors.aspx Biomarker
PIK3CA 5290 Sensitivity PIK3CA MUT/AMP ZSTK474 11647372 PI3K Inhibitors Clinical Trial Agents (For Ovarian and other Cancers) https://www.clearityfoundation.org/healthcare-pros/drugs-bio/clinicla-trial-agents-ovarian/pi3k-inhibitors.aspx Biomarker
PIK3CA 5290 Sensitivity PIK3CA MUT/AMP DS-7423 PI3K/mTOR Inhibitors Clinical Trial Agents (For Ovarian and other Cancers) https://www.clearityfoundation.org/healthcare-pros/drugs-bio/clinicla-trial-agents-ovarian/pi3k-inhibitors.aspx Biomarker
PIK3CA 5290 Sensitivity PIK3CA MUT/AMP GSK2126458 25167777 PI3K/mTOR Inhibitors Clinical Trial Agents (For Ovarian and other Cancers) https://www.clearityfoundation.org/healthcare-pros/drugs-bio/clinicla-trial-agents-ovarian/pi3k-inhibitors.aspx Biomarker
PIK3CA 5290 Sensitivity PIK3CA MUT/AMP NVP-BEZ235 11977753 PI3K/mTOR Inhibitors Clinical Trial Agents (For Ovarian and other Cancers) https://www.clearityfoundation.org/healthcare-pros/drugs-bio/clinicla-trial-agents-ovarian/pi3k-inhibitors.aspx Biomarker
PIK3CA 5290 Sensitivity PIK3CA MUT/AMP PF-04691502 25033539 PI3K/mTOR Inhibitors Clinical Trial Agents (For Ovarian and other Cancers) https://www.clearityfoundation.org/healthcare-pros/drugs-bio/clinicla-trial-agents-ovarian/pi3k-inhibitors.aspx Biomarker
PIK3CA 5290 Sensitivity PIK3CA MUT/AMP PF-05212384 25033539 PI3K/mTOR Inhibitors Clinical Trial Agents (For Ovarian and other Cancers) https://www.clearityfoundation.org/healthcare-pros/drugs-bio/clinicla-trial-agents-ovarian/pi3k-inhibitors.aspx Biomarker
PIK3CA 5290 Sensitivity PIK3CA MUT/AMP XL765 49867926 PI3K/mTOR Inhibitors Clinical Trial Agents (For Ovarian and other Cancers) https://www.clearityfoundation.org/healthcare-pros/drugs-bio/clinicla-trial-agents-ovarian/pi3k-inhibitors.aspx Biomarker
PIK3R1 5295 Sensitivity PIK3R1 MUT/DEL BAY80-6946 24989044 PI3K Inhibitors Clinical Trial Agents (For Ovarian and other Cancers) https://www.clearityfoundation.org/healthcare-pros/drugs-bio/clinicla-trial-agents-ovarian/pi3k-inhibitors.aspx Biomarker
PIK3R1 5295 Sensitivity PIK3R1 MUT/DEL BYL719 56649450 PI3K Inhibitors Clinical Trial Agents (For Ovarian and other Cancers) https://www.clearityfoundation.org/healthcare-pros/drugs-bio/clinicla-trial-agents-ovarian/pi3k-inhibitors.aspx Biomarker
PIK3R1 5295 Sensitivity PIK3R1 MUT/DEL XL-147 1893730 PI3K Inhibitors Clinical Trial Agents (For Ovarian and other Cancers) https://www.clearityfoundation.org/healthcare-pros/drugs-bio/clinicla-trial-agents-ovarian/pi3k-inhibitors.aspx Biomarker
PIK3R1 5295 Sensitivity PIK3R1 MUT/DEL ZSTK474 11647372 PI3K Inhibitors Clinical Trial Agents (For Ovarian and other Cancers) https://www.clearityfoundation.org/healthcare-pros/drugs-bio/clinicla-trial-agents-ovarian/pi3k-inhibitors.aspx Biomarker
PIK3R1 5295 Sensitivity PIK3R1 MUT/DEL DS-7423 PI3K/mTOR Inhibitors Clinical Trial Agents (For Ovarian and other Cancers) https://www.clearityfoundation.org/healthcare-pros/drugs-bio/clinicla-trial-agents-ovarian/pi3k-inhibitors.aspx Biomarker
PIK3R1 5295 Sensitivity PIK3R1 MUT/DEL GSK2126458 25167777 PI3K/mTOR Inhibitors Clinical Trial Agents (For Ovarian and other Cancers) https://www.clearityfoundation.org/healthcare-pros/drugs-bio/clinicla-trial-agents-ovarian/pi3k-inhibitors.aspx Biomarker
PIK3R1 5295 Sensitivity PIK3R1 MUT/DEL NVP-BEZ235 11977753 PI3K/mTOR Inhibitors Clinical Trial Agents (For Ovarian and other Cancers) https://www.clearityfoundation.org/healthcare-pros/drugs-bio/clinicla-trial-agents-ovarian/pi3k-inhibitors.aspx Biomarker
PIK3R1 5295 Sensitivity PIK3R1 MUT/DEL PF-04691502 25033539 PI3K/mTOR Inhibitors Clinical Trial Agents (For Ovarian and other Cancers) https://www.clearityfoundation.org/healthcare-pros/drugs-bio/clinicla-trial-agents-ovarian/pi3k-inhibitors.aspx Biomarker
PIK3R1 5295 Sensitivity PIK3R1 MUT/DEL PF-05212384 25033539 PI3K/mTOR Inhibitors Clinical Trial Agents (For Ovarian and other Cancers) https://www.clearityfoundation.org/healthcare-pros/drugs-bio/clinicla-trial-agents-ovarian/pi3k-inhibitors.aspx Biomarker
PIK3R1 5295 Sensitivity PIK3R1 MUT/DEL XL765 49867926 PI3K/mTOR Inhibitors Clinical Trial Agents (For Ovarian and other Cancers) https://www.clearityfoundation.org/healthcare-pros/drugs-bio/clinicla-trial-agents-ovarian/pi3k-inhibitors.aspx Biomarker
PTEN 5728 Resistance PTEN Loss Cetuximab Erbitux 56842117 EGFR Inhibitors Clinical Trial Agents (Approved in other Cancers) https://www.clearityfoundation.org/healthcare-pros/drugs-bio/clinicla-trial-agents/egfr-inhibitors.aspx Biomarker
PTEN 5728 Resistance PTEN Loss Erlotinib Tarceva 176870 EGFR Inhibitors Clinical Trial Agents (Approved in other Cancers) https://www.clearityfoundation.org/healthcare-pros/drugs-bio/clinicla-trial-agents/egfr-inhibitors.aspx Biomarker
PTEN 5728 Resistance PTEN Loss Gefitinib Iressa 123631 EGFR Inhibitors Clinical Trial Agents (Approved in other Cancers) https://www.clearityfoundation.org/healthcare-pros/drugs-bio/clinicla-trial-agents/egfr-inhibitors.aspx Biomarker
PTEN 5728 Resistance PTEN Loss Panitumumab Vectibix EGFR Inhibitors Clinical Trial Agents (Approved in other Cancers) https://www.clearityfoundation.org/healthcare-pros/drugs-bio/clinicla-trial-agents/egfr-inhibitors.aspx Biomarker
PTEN 5728 Resistance PTEN Loss Vandetanib Capreisa 3081361 EGFR Inhibitors Clinical Trial Agents (Approved in other Cancers) https://www.clearityfoundation.org/healthcare-pros/drugs-bio/clinicla-trial-agents/egfr-inhibitors.aspx Biomarker
PTEN 5728 Sensitivity PTEN Loss Everolimus Afinitor 6442177 mTOR Inhibitors Clinical Trial Agents (Approved in other Cancers) https://www.clearityfoundation.org/healthcare-pros/drugs-bio/clinicla-trial-agents/mtor-inhibitors.aspx Biomarker
PTEN 5728 Sensitivity PTEN Loss Temsirolimus Torisel 6918289 mTOR Inhibitors Clinical Trial Agents (Approved in other Cancers) https://www.clearityfoundation.org/healthcare-pros/drugs-bio/clinicla-trial-agents/mtor-inhibitors.aspx Biomarker
PTEN 5728 Sensitivity PTEN MUT/DEL/LOSS BAY80-6946 24989044 PI3K Inhibitors Clinical Trial Agents (For Ovarian and other Cancers) https://www.clearityfoundation.org/healthcare-pros/drugs-bio/clinicla-trial-agents-ovarian/pi3k-inhibitors.aspx Biomarker
PTEN 5728 Sensitivity PTEN MUT/DEL/LOSS BYL719 56649450 PI3K Inhibitors Clinical Trial Agents (For Ovarian and other Cancers) https://www.clearityfoundation.org/healthcare-pros/drugs-bio/clinicla-trial-agents-ovarian/pi3k-inhibitors.aspx Biomarker
PTEN 5728 Sensitivity PTEN MUT/DEL/LOSS XL-147 1893730 PI3K Inhibitors Clinical Trial Agents (For Ovarian and other Cancers) https://www.clearityfoundation.org/healthcare-pros/drugs-bio/clinicla-trial-agents-ovarian/pi3k-inhibitors.aspx Biomarker
PTEN 5728 Sensitivity PTEN MUT/DEL/LOSS ZSTK474 11647372 PI3K Inhibitors Clinical Trial Agents (For Ovarian and other Cancers) https://www.clearityfoundation.org/healthcare-pros/drugs-bio/clinicla-trial-agents-ovarian/pi3k-inhibitors.aspx Biomarker
PTEN 5728 Sensitivity PTEN MUT/DEL/LOSS DS-7423 PI3K/mTOR Inhibitors Clinical Trial Agents (For Ovarian and other Cancers) https://www.clearityfoundation.org/healthcare-pros/drugs-bio/clinicla-trial-agents-ovarian/pi3k-inhibitors.aspx Biomarker
PTEN 5728 Sensitivity PTEN MUT/DEL/LOSS GSK2126458 25167777 PI3K/mTOR Inhibitors Clinical Trial Agents (For Ovarian and other Cancers) https://www.clearityfoundation.org/healthcare-pros/drugs-bio/clinicla-trial-agents-ovarian/pi3k-inhibitors.aspx Biomarker
PTEN 5728 Sensitivity PTEN MUT/DEL/LOSS NVP-BEZ235 11977753 PI3K/mTOR Inhibitors Clinical Trial Agents (For Ovarian and other Cancers) https://www.clearityfoundation.org/healthcare-pros/drugs-bio/clinicla-trial-agents-ovarian/pi3k-inhibitors.aspx Biomarker
PTEN 5728 Sensitivity PTEN MUT/DEL/LOSS PF-04691502 25033539 PI3K/mTOR Inhibitors Clinical Trial Agents (For Ovarian and other Cancers) https://www.clearityfoundation.org/healthcare-pros/drugs-bio/clinicla-trial-agents-ovarian/pi3k-inhibitors.aspx Biomarker
PTEN 5728 Sensitivity PTEN MUT/DEL/LOSS PF-05212384 25033539 PI3K/mTOR Inhibitors Clinical Trial Agents (For Ovarian and other Cancers) https://www.clearityfoundation.org/healthcare-pros/drugs-bio/clinicla-trial-agents-ovarian/pi3k-inhibitors.aspx Biomarker
PTEN 5728 Sensitivity PTEN MUT/DEL/LOSS XL765 49867926 PI3K/mTOR Inhibitors Clinical Trial Agents (For Ovarian and other Cancers) https://www.clearityfoundation.org/healthcare-pros/drugs-bio/clinicla-trial-agents-ovarian/pi3k-inhibitors.aspx Biomarker
RRM1 6240 Resistance RRM1 Gemcitabine Gemzar 60750 Nucleoside Analogs Cytotoxic Drugs https://www.clearityfoundation.org/healthcare-pros/drugs-bio/cytotoxic-drugs/nucleoside.aspx Biomarker
SPARC 6678 Sensitivity SPARC Nab-paclitaxel Abraxane 36314 Taxanes Cytotoxic Drugs https://www.clearityfoundation.org/healthcare-pros/drugs-bio/cytotoxic-drugs/taxanes.aspx Biomarker
TLE3 7090 Sensitivity TLE3 Docetaxel Taxotere 148124 Taxanes Cytotoxic Drugs https://www.clearityfoundation.org/healthcare-pros/drugs-bio/cytotoxic-drugs/taxanes.aspx Biomarker
TLE3 7090 Sensitivity TLE3 Paclitaxel Taxol 36314 Taxanes Cytotoxic Drugs https://www.clearityfoundation.org/healthcare-pros/drugs-bio/cytotoxic-drugs/taxanes.aspx Biomarker
TOP1 7150 Sensitivity TOPO1 Irinotecan Camptosar 60838 Topoisomerase 1 Inhibitors Cytotoxic Drugs https://www.clearityfoundation.org/healthcare-pros/drugs-bio/cytotoxic-drugs/topo-i.aspx Biomarker
TOP1 7150 Sensitivity TOPO1 Topotecan Hycamtin 60700 Topoisomerase 1 Inhibitors Cytotoxic Drugs https://www.clearityfoundation.org/healthcare-pros/drugs-bio/cytotoxic-drugs/topo-i.aspx Biomarker
TOP2A 7153 Sensitivity TOP2A Liposomal doxorubicin Doxil 31703 Topoisomerase 2 Inhibitors Cytotoxic Drugs https://www.clearityfoundation.org/healthcare-pros/drugs-bio/cytotoxic-drugs/topo-ii.aspx Biomarker
TOP2A 7153 Sensitivity TOP2A Liposomal doxorubicin Doxil 31703 Topoisomerase 2 Inhibitors Cytotoxic Drugs https://www.clearityfoundation.org/healthcare-pros/drugs-bio/cytotoxic-drugs/topo-ii.aspx Biomarker
TUBB3 10381 Resistance TUBB3 Docetaxel Taxotere 148124 Taxanes Cytotoxic Drugs https://www.clearityfoundation.org/healthcare-pros/drugs-bio/cytotoxic-drugs/taxanes.aspx Biomarker
TUBB3 10381 Resistance TUBB3 Paclitaxel Taxol 36314 Taxanes Cytotoxic Drugs https://www.clearityfoundation.org/healthcare-pros/drugs-bio/cytotoxic-drugs/taxanes.aspx Biomarker
TYMS 7298 Resistance TS Pemetrexed Alimta 446556 Anti-Folates Cytotoxic Drugs https://www.clearityfoundation.org/healthcare-pros/drugs-bio/cytotoxic-drugs/fluoropyrimidines.aspx Biomarker
TYMS 7298 Sensitivity TS Capecitabine Xeloda 60953 F-pyrimidines Cytotoxic Drugs https://www.clearityfoundation.org/healthcare-pros/drugs-bio/cytotoxic-drugs/fluoropyrimidines.aspx Biomarker