KarrLab/wc_onto

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wc_onto/ontologies/KISAO.owl

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<?xml version="1.0"?>
<rdf:RDF xmlns="http://www.biomodels.net/kisao/KISAO_FULL#"
     xml:base="http://www.biomodels.net/kisao/KISAO_FULL"
     xmlns:dc="http://purl.org/dc/terms/"
     xmlns:obo="http://purl.obolibrary.org/obo/"
     xmlns:ont="http://www.co-ode.org/ontologies/ont.owl#"
     xmlns:owl="http://www.w3.org/2002/07/owl#"
     xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#"
     xmlns:xml="http://www.w3.org/XML/1998/namespace"
     xmlns:xsd="http://www.w3.org/2001/XMLSchema#"
     xmlns:rdfs="http://www.w3.org/2000/01/rdf-schema#"
     xmlns:skos="http://www.w3.org/2004/02/skos/core#"
     xmlns:kisao="http://www.biomodels.net/kisao/KISAO#"
     xmlns:protege="http://protege.stanford.edu/plugins/owl/protege#"
     xmlns:oboInOwl="http://www.geneontology.org/formats/oboInOwl#">
    <owl:Ontology rdf:about="http://www.biomodels.net/kisao/KISAO_FULL#">
        <owl:imports rdf:resource="http://www.biomodels.net/kisao/KISAO#"/>
        <dc:rights>Artistic License 2.0</dc:rights>
        <rdfs:comment xml:lang="en">Kinetic Simulation Algorithm Ontology (full version, containing deprecated classes)</rdfs:comment>
        <rdfs:seeAlso rdf:datatype="http://www.w3.org/2001/XMLSchema#anyURI">http://co.mbine.org/standards/kisao</rdfs:seeAlso>
        <rdfs:seeAlso rdf:datatype="http://www.w3.org/2001/XMLSchema#anyURI">http://identifiers.org/pubmed/22027554</rdfs:seeAlso>
        <owl:versionInfo rdf:datatype="http://www.w3.org/2001/XMLSchema#decimal">2.5</owl:versionInfo>
        <skos:definition xml:lang="en">The Kinetic Simulation Algorithm Ontology (KiSAO) classifies algorithms available for the simulation and analysis of models in biology, and their characteristics and the parameters required for their use.</skos:definition>
    </owl:Ontology>
    


    <!-- 
    ///////////////////////////////////////////////////////////////////////////////////////
    //
    // Annotation properties
    //
    ///////////////////////////////////////////////////////////////////////////////////////
     -->

    


    <!-- http://www.geneontology.org/formats/oboInOwl#Comment -->

    <owl:AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#Comment"/>
    


    <!-- http://www.geneontology.org/formats/oboInOwl#CreatedBy -->

    <owl:AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#CreatedBy"/>
    


    <!-- http://www.geneontology.org/formats/oboInOwl#CreationDate -->

    <owl:AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#CreationDate"/>
    


    <!-- http://www.geneontology.org/formats/oboInOwl#Namespace -->

    <owl:AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#Namespace"/>
    


    <!-- http://www.geneontology.org/formats/oboInOwl#OwlDef -->

    <owl:AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#OwlDef"/>
    


    <!-- 
    ///////////////////////////////////////////////////////////////////////////////////////
    //
    // Object Properties
    //
    ///////////////////////////////////////////////////////////////////////////////////////
     -->

    


    <!-- http://www.biomodels.net/kisao/KISAO#KISAO_0000247 -->

    <owl:ObjectProperty rdf:about="http://www.biomodels.net/kisao/KISAO#KISAO_0000247">
        <rdfs:domain rdf:resource="http://www.biomodels.net/kisao/KISAO#KISAO_0000000"/>
        <rdfs:range rdf:resource="http://www.biomodels.net/kisao/KISAO#KISAO_0000097"/>
        <oboInOwl:Namespace xml:lang="en">KISAO_DEPRECATED</oboInOwl:Namespace>
        <oboInOwl:OwlDef>?X subclassOf not (KISAO_0000245 some ?Y)</oboInOwl:OwlDef>
        <rdfs:comment xml:lang="en">lacksProperty is an alias for not hasProperty. It should not be used in OWL version of KiSAO. It&apos;s used in OBO version of KiSAO, as it is not possible to represent negation in OBO.</rdfs:comment>
        <rdfs:label xml:lang="en">lacks property</rdfs:label>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:ObjectProperty>
    


    <!-- 
    ///////////////////////////////////////////////////////////////////////////////////////
    //
    // Classes
    //
    ///////////////////////////////////////////////////////////////////////////////////////
     -->

    


    <!-- http://www.biomodels.net/kisao/KISAO#KISAO_0000001 -->

    <owl:Class rdf:about="http://www.biomodels.net/kisao/KISAO#KISAO_0000001">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://www.biomodels.net/kisao/KISAO#KISAO_0000025"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://www.biomodels.net/kisao/KISAO#KISAO_0000245"/>
                        <owl:someValuesFrom rdf:resource="http://www.biomodels.net/kisao/KISAO#KISAO_0000237"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://www.biomodels.net/kisao/KISAO#KISAO_0000025"/>
        <kisao:isOrganizational rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</kisao:isOrganizational>
        <oboInOwl:Namespace xml:lang="en">KISAO_DEPRECATED</oboInOwl:Namespace>
        <rdfs:label xml:lang="en">Gillespie-like approximate stochastic simulation method</rdfs:label>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://www.biomodels.net/kisao/KISAO#KISAO_0000002 -->

    <owl:Class rdf:about="http://www.biomodels.net/kisao/KISAO#KISAO_0000002">
        <rdfs:subClassOf rdf:resource="http://www.biomodels.net/kisao/KISAO#KISAO_0000262"/>
        <rdfs:subClassOf>
            <owl:Class>
                <owl:complementOf>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://www.biomodels.net/kisao/KISAO#KISAO_0000245"/>
                        <owl:someValuesFrom rdf:resource="http://www.biomodels.net/kisao/KISAO#KISAO_0000102"/>
                    </owl:Restriction>
                </owl:complementOf>
            </owl:Class>
        </rdfs:subClassOf>
        <kisao:isOrganizational rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</kisao:isOrganizational>
        <oboInOwl:Namespace xml:lang="en">KISAO_DEPRECATED</oboInOwl:Namespace>
        <rdfs:label xml:lang="en">non-spatial tau-leaping method</rdfs:label>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://www.biomodels.net/kisao/KISAO#KISAO_0000016 -->

    <owl:Class rdf:about="http://www.biomodels.net/kisao/KISAO#KISAO_0000016">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://www.biomodels.net/kisao/KISAO#KISAO_0000000"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://www.biomodels.net/kisao/KISAO#KISAO_0000245"/>
                        <owl:someValuesFrom rdf:resource="http://www.biomodels.net/kisao/KISAO#KISAO_0000105"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://www.biomodels.net/kisao/KISAO#KISAO_0000262"/>
        <kisao:isOrganizational rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</kisao:isOrganizational>
        <oboInOwl:CreatedBy xml:lang="en">NLN</oboInOwl:CreatedBy>
        <oboInOwl:CreationDate rdf:datatype="http://www.w3.org/2001/XMLSchema#date">2008-07-08</oboInOwl:CreationDate>
        <oboInOwl:Namespace xml:lang="en">KISAO_DEPRECATED</oboInOwl:Namespace>
        <rdfs:comment xml:lang="en">Algorithm that allows to change the values of a system&apos;s variables by discrete (integral) amounts.</rdfs:comment>
        <rdfs:label xml:lang="en">algorithm using discrete variables</rdfs:label>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://www.biomodels.net/kisao/KISAO#KISAO_0000018 -->

    <owl:Class rdf:about="http://www.biomodels.net/kisao/KISAO#KISAO_0000018">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://www.biomodels.net/kisao/KISAO#KISAO_0000000"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://www.biomodels.net/kisao/KISAO#KISAO_0000245"/>
                        <owl:someValuesFrom rdf:resource="http://www.biomodels.net/kisao/KISAO#KISAO_0000106"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://www.biomodels.net/kisao/KISAO#KISAO_0000262"/>
        <kisao:isOrganizational rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</kisao:isOrganizational>
        <oboInOwl:CreatedBy xml:lang="en">NLN</oboInOwl:CreatedBy>
        <oboInOwl:CreationDate rdf:datatype="http://www.w3.org/2001/XMLSchema#date">2008-07-08</oboInOwl:CreationDate>
        <oboInOwl:Namespace xml:lang="en">KISAO_DEPRECATED</oboInOwl:Namespace>
        <rdfs:comment xml:lang="en">Algorithm that allows to change the values of a system&apos;s variables by continuous (non-integral) amounts.</rdfs:comment>
        <rdfs:label xml:lang="en">algorithm using continuous variables</rdfs:label>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://www.biomodels.net/kisao/KISAO#KISAO_0000023 -->

    <owl:Class rdf:about="http://www.biomodels.net/kisao/KISAO#KISAO_0000023">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://www.biomodels.net/kisao/KISAO#KISAO_0000000"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://www.biomodels.net/kisao/KISAO#KISAO_0000245"/>
                        <owl:someValuesFrom rdf:resource="http://www.biomodels.net/kisao/KISAO#KISAO_0000102"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://www.biomodels.net/kisao/KISAO#KISAO_0000262"/>
        <kisao:isOrganizational rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</kisao:isOrganizational>
        <oboInOwl:CreatedBy xml:lang="en">NLN</oboInOwl:CreatedBy>
        <oboInOwl:CreationDate rdf:datatype="http://www.w3.org/2001/XMLSchema#date">2008-07-08</oboInOwl:CreationDate>
        <oboInOwl:Namespace xml:lang="en">KISAO_DEPRECATED</oboInOwl:Namespace>
        <rdfs:comment xml:lang="en">Algorithm that takes into account the location of the reacting components.</rdfs:comment>
        <rdfs:label xml:lang="en">algorithm using spatial description</rdfs:label>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://www.biomodels.net/kisao/KISAO#KISAO_0000024 -->

    <owl:Class rdf:about="http://www.biomodels.net/kisao/KISAO#KISAO_0000024">
        <rdfs:subClassOf rdf:resource="http://www.biomodels.net/kisao/KISAO#KISAO_0000262"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://www.biomodels.net/kisao/KISAO#KISAO_0000245"/>
                <owl:someValuesFrom rdf:resource="http://www.biomodels.net/kisao/KISAO#KISAO_0000102"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://www.biomodels.net/kisao/KISAO#KISAO_0000245"/>
                <owl:someValuesFrom rdf:resource="http://www.biomodels.net/kisao/KISAO#KISAO_0000103"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://www.biomodels.net/kisao/KISAO#KISAO_0000245"/>
                <owl:someValuesFrom rdf:resource="http://www.biomodels.net/kisao/KISAO#KISAO_0000106"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <kisao:isOrganizational rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</kisao:isOrganizational>
        <oboInOwl:CreatedBy xml:lang="en">NLN</oboInOwl:CreatedBy>
        <oboInOwl:CreationDate rdf:datatype="http://www.w3.org/2001/XMLSchema#date">2008-07-08</oboInOwl:CreationDate>
        <oboInOwl:Namespace xml:lang="en">KISAO_DEPRECATED</oboInOwl:Namespace>
        <rdfs:comment xml:lang="en">Partial differential equations are used to describe variations in concentrations over both, space and time.</rdfs:comment>
        <rdfs:label xml:lang="en">partial differential equation method</rdfs:label>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://www.biomodels.net/kisao/KISAO#KISAO_0000025 -->

    <owl:Class rdf:about="http://www.biomodels.net/kisao/KISAO#KISAO_0000025">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://www.biomodels.net/kisao/KISAO#KISAO_0000241"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://www.biomodels.net/kisao/KISAO#KISAO_0000245"/>
                        <owl:someValuesFrom rdf:resource="http://www.biomodels.net/kisao/KISAO#KISAO_0000104"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://www.biomodels.net/kisao/KISAO#KISAO_0000262"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://www.biomodels.net/kisao/KISAO#KISAO_0000245"/>
                <owl:someValuesFrom rdf:resource="http://www.biomodels.net/kisao/KISAO#KISAO_0000104"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://www.biomodels.net/kisao/KISAO#KISAO_0000245"/>
                <owl:someValuesFrom rdf:resource="http://www.biomodels.net/kisao/KISAO#KISAO_0000105"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://www.biomodels.net/kisao/KISAO#KISAO_0000245"/>
                <owl:someValuesFrom rdf:resource="http://www.biomodels.net/kisao/KISAO#KISAO_0000107"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <kisao:isOrganizational rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</kisao:isOrganizational>
        <oboInOwl:Comment xml:lang="en">This definition is dodgy, as is the name of the term. That will do for the moment, until we redesign the whole stochastic branch, based on algorithm details.</oboInOwl:Comment>
        <oboInOwl:CreatedBy xml:lang="en">NLN</oboInOwl:CreatedBy>
        <oboInOwl:CreationDate rdf:datatype="http://www.w3.org/2001/XMLSchema#date">2008-07-08</oboInOwl:CreationDate>
        <oboInOwl:Namespace xml:lang="en">KISAO_DEPRECATED</oboInOwl:Namespace>
        <rdfs:comment xml:lang="en">Stochastic simulation algorithm using the an approach alike the one described in Gillespie&apos;s papers of 1976 and 1977.</rdfs:comment>
        <rdfs:label xml:lang="en">Gillespie-like stochastic simulation method</rdfs:label>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://www.biomodels.net/kisao/KISAO#KISAO_0000026 -->

    <owl:Class rdf:about="http://www.biomodels.net/kisao/KISAO#KISAO_0000026">
        <rdfs:subClassOf rdf:resource="http://www.biomodels.net/kisao/KISAO#KISAO_0000262"/>
        <kisao:isOrganizational rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</kisao:isOrganizational>
        <oboInOwl:CreatedBy xml:lang="en">NLN</oboInOwl:CreatedBy>
        <oboInOwl:CreationDate rdf:datatype="http://www.w3.org/2001/XMLSchema#date">2008-07-08</oboInOwl:CreationDate>
        <oboInOwl:Namespace xml:lang="en">KISAO_DEPRECATED</oboInOwl:Namespace>
        <rdfs:comment xml:lang="en">Algorithms that considers the system to be simulated as made of well-stirred components, that is the activity of the components is the same independently of their location.</rdfs:comment>
        <rdfs:label xml:lang="en">algorithm using non-spatial description</rdfs:label>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://www.biomodels.net/kisao/KISAO#KISAO_0000034 -->

    <owl:Class rdf:about="http://www.biomodels.net/kisao/KISAO#KISAO_0000034">
        <rdfs:subClassOf rdf:resource="http://www.biomodels.net/kisao/KISAO#KISAO_0000262"/>
        <rdfs:subClassOf rdf:resource="http://www.biomodels.net/kisao/KISAO#KISAO_0000333"/>
        <rdfs:subClassOf>
            <owl:Class>
                <owl:complementOf>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://www.biomodels.net/kisao/KISAO#KISAO_0000245"/>
                        <owl:someValuesFrom rdf:resource="http://www.biomodels.net/kisao/KISAO#KISAO_0000102"/>
                    </owl:Restriction>
                </owl:complementOf>
            </owl:Class>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://www.biomodels.net/kisao/KISAO#KISAO_0000245"/>
                <owl:someValuesFrom rdf:resource="http://www.biomodels.net/kisao/KISAO#KISAO_0000236"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <kisao:isOrganizational rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</kisao:isOrganizational>
        <oboInOwl:CreatedBy xml:lang="en">NLN</oboInOwl:CreatedBy>
        <oboInOwl:CreationDate rdf:datatype="http://www.w3.org/2001/XMLSchema#date">2008-07-08</oboInOwl:CreationDate>
        <oboInOwl:Namespace xml:lang="en">KISAO_DEPRECATED</oboInOwl:Namespace>
        <rdfs:comment xml:lang="en">Algorithm aimed to speed-up Gillespie&apos;s direct method.</rdfs:comment>
        <rdfs:label xml:lang="en">optimized direct method</rdfs:label>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://www.biomodels.net/kisao/KISAO#KISAO_0000035 -->

    <owl:Class rdf:about="http://www.biomodels.net/kisao/KISAO#KISAO_0000035">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://www.biomodels.net/kisao/KISAO#KISAO_0000000"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://www.biomodels.net/kisao/KISAO#KISAO_0000245"/>
                        <owl:someValuesFrom rdf:resource="http://www.biomodels.net/kisao/KISAO#KISAO_0000103"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://www.biomodels.net/kisao/KISAO#KISAO_0000262"/>
        <kisao:isOrganizational rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</kisao:isOrganizational>
        <oboInOwl:CreatedBy xml:lang="en">NLN</oboInOwl:CreatedBy>
        <oboInOwl:CreationDate rdf:datatype="http://www.w3.org/2001/XMLSchema#date">2008-07-08</oboInOwl:CreationDate>
        <oboInOwl:Namespace xml:lang="en">KISAO_DEPRECATED</oboInOwl:Namespace>
        <rdfs:comment xml:lang="en">Algorithm that simulates the temporal evolution of a system using determined descriptions, that from a precise initial state always provide the same ending state.</rdfs:comment>
        <rdfs:label xml:lang="en">algorithm using deterministic rules</rdfs:label>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://www.biomodels.net/kisao/KISAO#KISAO_0000036 -->

    <owl:Class rdf:about="http://www.biomodels.net/kisao/KISAO#KISAO_0000036">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://www.biomodels.net/kisao/KISAO#KISAO_0000000"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://www.biomodels.net/kisao/KISAO#KISAO_0000245"/>
                        <owl:someValuesFrom rdf:resource="http://www.biomodels.net/kisao/KISAO#KISAO_0000104"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://www.biomodels.net/kisao/KISAO#KISAO_0000262"/>
        <kisao:isOrganizational rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</kisao:isOrganizational>
        <oboInOwl:CreatedBy xml:lang="en">NLN</oboInOwl:CreatedBy>
        <oboInOwl:CreationDate rdf:datatype="http://www.w3.org/2001/XMLSchema#date">2008-07-08</oboInOwl:CreationDate>
        <oboInOwl:Namespace xml:lang="en">KISAO_DEPRECATED</oboInOwl:Namespace>
        <rdfs:comment xml:lang="en">Algorithm that simulates the temporal evolution of a system using probabilistic rules, that from a precise initial state may provide different ending state.</rdfs:comment>
        <rdfs:label xml:lang="en">algorithm using stochastic rules</rdfs:label>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://www.biomodels.net/kisao/KISAO#KISAO_0000037 -->

    <owl:Class rdf:about="http://www.biomodels.net/kisao/KISAO#KISAO_0000037">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://www.biomodels.net/kisao/KISAO#KISAO_0000000"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://www.biomodels.net/kisao/KISAO#KISAO_0000245"/>
                        <owl:someValuesFrom rdf:resource="http://www.biomodels.net/kisao/KISAO#KISAO_0000108"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://www.biomodels.net/kisao/KISAO#KISAO_0000262"/>
        <kisao:isOrganizational rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</kisao:isOrganizational>
        <oboInOwl:CreatedBy xml:lang="en">NLN</oboInOwl:CreatedBy>
        <oboInOwl:CreationDate rdf:datatype="http://www.w3.org/2001/XMLSchema#date">2008-07-08</oboInOwl:CreationDate>
        <oboInOwl:Namespace xml:lang="en">KISAO_DEPRECATED</oboInOwl:Namespace>
        <rdfs:comment xml:lang="en">Algorithm that uses timesteps of constant length to update the state of a system during the whole simulation.</rdfs:comment>
        <rdfs:label xml:lang="en">algorithm using fixed timesteps</rdfs:label>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://www.biomodels.net/kisao/KISAO#KISAO_0000041 -->

    <owl:Class rdf:about="http://www.biomodels.net/kisao/KISAO#KISAO_0000041">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://www.biomodels.net/kisao/KISAO#KISAO_0000000"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://www.biomodels.net/kisao/KISAO#KISAO_0000245"/>
                        <owl:someValuesFrom rdf:resource="http://www.biomodels.net/kisao/KISAO#KISAO_0000107"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://www.biomodels.net/kisao/KISAO#KISAO_0000262"/>
        <kisao:isOrganizational rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</kisao:isOrganizational>
        <oboInOwl:CreatedBy xml:lang="en">NLN</oboInOwl:CreatedBy>
        <oboInOwl:CreationDate rdf:datatype="http://www.w3.org/2001/XMLSchema#date">2008-07-08</oboInOwl:CreationDate>
        <oboInOwl:Namespace xml:lang="en">KISAO_DEPRECATED</oboInOwl:Namespace>
        <rdfs:comment xml:lang="en">Algorithm that does not use fixed timesteps to update the state of a system during the whole simulation, but on the contrary adapts the length of the timesteps to the local situation.</rdfs:comment>
        <rdfs:label xml:lang="en">algorithm using adaptive timesteps</rdfs:label>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://www.biomodels.net/kisao/KISAO#KISAO_0000042 -->

    <owl:Class rdf:about="http://www.biomodels.net/kisao/KISAO#KISAO_0000042">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://www.biomodels.net/kisao/KISAO#KISAO_0000241"/>
                    <owl:Class>
                        <owl:complementOf>
                            <owl:Restriction>
                                <owl:onProperty rdf:resource="http://www.biomodels.net/kisao/KISAO#KISAO_0000245"/>
                                <owl:someValuesFrom rdf:resource="http://www.biomodels.net/kisao/KISAO#KISAO_0000102"/>
                            </owl:Restriction>
                        </owl:complementOf>
                    </owl:Class>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://www.biomodels.net/kisao/KISAO#KISAO_0000262"/>
        <kisao:isOrganizational rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</kisao:isOrganizational>
        <oboInOwl:Namespace xml:lang="en">KISAO_DEPRECATED</oboInOwl:Namespace>
        <rdfs:label xml:lang="en">Non-spatial Gillespie-like method</rdfs:label>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://www.biomodels.net/kisao/KISAO#KISAO_0000044 -->

    <owl:Class rdf:about="http://www.biomodels.net/kisao/KISAO#KISAO_0000044">
        <rdfs:subClassOf rdf:resource="http://www.biomodels.net/kisao/KISAO#KISAO_0000262"/>
        <kisao:isOrganizational rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</kisao:isOrganizational>
        <oboInOwl:Namespace xml:lang="en">KISAO_DEPRECATED</oboInOwl:Namespace>
        <rdfs:label xml:lang="en">Gillespie based method for stiff systems.</rdfs:label>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://www.biomodels.net/kisao/KISAO#KISAO_0000079 -->

    <owl:Class rdf:about="http://www.biomodels.net/kisao/KISAO#KISAO_0000079">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://www.biomodels.net/kisao/KISAO#KISAO_0000039"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://www.biomodels.net/kisao/KISAO#KISAO_0000245"/>
                        <owl:someValuesFrom rdf:resource="http://www.biomodels.net/kisao/KISAO#KISAO_0000239"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://www.biomodels.net/kisao/KISAO#KISAO_0000262"/>
        <kisao:isOrganizational rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</kisao:isOrganizational>
        <oboInOwl:Namespace xml:lang="en">KISAO_DEPRECATED</oboInOwl:Namespace>
        <rdfs:comment xml:lang="en">Explicit tau-leaping method.</rdfs:comment>
        <rdfs:label xml:lang="en">explicit tau-leaping method</rdfs:label>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://www.biomodels.net/kisao/KISAO#KISAO_0000083 -->

    <owl:Class rdf:about="http://www.biomodels.net/kisao/KISAO#KISAO_0000083">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://www.biomodels.net/kisao/KISAO#KISAO_0000039"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://www.biomodels.net/kisao/KISAO#KISAO_0000245"/>
                        <owl:someValuesFrom rdf:resource="http://www.biomodels.net/kisao/KISAO#KISAO_0000240"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://www.biomodels.net/kisao/KISAO#KISAO_0000262"/>
        <kisao:isOrganizational rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</kisao:isOrganizational>
        <oboInOwl:Namespace xml:lang="en">KISAO_DEPRECATED</oboInOwl:Namespace>
        <rdfs:comment xml:lang="en">Implicit tau-leaping method.</rdfs:comment>
        <rdfs:label xml:lang="en">implicit tau-leaping method</rdfs:label>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://www.biomodels.net/kisao/KISAO#KISAO_0000096 -->

    <owl:Class rdf:about="http://www.biomodels.net/kisao/KISAO#KISAO_0000096">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://www.biomodels.net/kisao/KISAO#KISAO_0000241"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://www.biomodels.net/kisao/KISAO#KISAO_0000245"/>
                        <owl:someValuesFrom rdf:resource="http://www.biomodels.net/kisao/KISAO#KISAO_0000104"/>
                    </owl:Restriction>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://www.biomodels.net/kisao/KISAO#KISAO_0000245"/>
                        <owl:someValuesFrom rdf:resource="http://www.biomodels.net/kisao/KISAO#KISAO_0000236"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://www.biomodels.net/kisao/KISAO#KISAO_0000262"/>
        <kisao:isOrganizational rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</kisao:isOrganizational>
        <oboInOwl:CreatedBy xml:lang="en">NLN</oboInOwl:CreatedBy>
        <oboInOwl:CreationDate rdf:datatype="http://www.w3.org/2001/XMLSchema#date">2008-07-14</oboInOwl:CreationDate>
        <oboInOwl:Namespace xml:lang="en">KISAO_DEPRECATED</oboInOwl:Namespace>
        <rdfs:comment xml:lang="en">Gillespie-like algorithm that produces exact realisation of the vector of entity amounts at each time by choosing rigorously time and reaction at each iteration.</rdfs:comment>
        <rdfs:label xml:lang="en">Gillespie-like exact stochastic simulation method</rdfs:label>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://www.biomodels.net/kisao/KISAO#KISAO_0000262 -->

    <owl:Class rdf:about="http://www.biomodels.net/kisao/KISAO#KISAO_0000262">
        <kisao:isOrganizational rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</kisao:isOrganizational>
        <oboInOwl:CreatedBy xml:lang="en">AZ</oboInOwl:CreatedBy>
        <oboInOwl:Namespace>KISAO_DEPRECATED</oboInOwl:Namespace>
        <rdfs:comment xml:lang="en">The root of the branch where all the deprecated terms are stored.</rdfs:comment>
        <rdfs:label xml:lang="en">deprecated class</rdfs:label>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://www.biomodels.net/kisao/KISAO#KISAO_0000284 -->

    <owl:Class rdf:about="http://www.biomodels.net/kisao/KISAO#KISAO_0000284">
        <owl:equivalentClass>
            <owl:Class>
                <owl:unionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://www.biomodels.net/kisao/KISAO#KISAO_0000019"/>
                    <rdf:Description rdf:about="http://www.biomodels.net/kisao/KISAO#KISAO_0000020"/>
                    <rdf:Description rdf:about="http://www.biomodels.net/kisao/KISAO#KISAO_0000282"/>
                    <rdf:Description rdf:about="http://www.biomodels.net/kisao/KISAO#KISAO_0000283"/>
                    <rdf:Description rdf:about="http://www.biomodels.net/kisao/KISAO#KISAO_0000355"/>
                    <rdf:Description rdf:about="http://www.biomodels.net/kisao/KISAO#KISAO_0000356"/>
                </owl:unionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://www.biomodels.net/kisao/KISAO#KISAO_0000000"/>
        <rdfs:subClassOf>
            <owl:Class>
                <owl:complementOf>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://www.biomodels.net/kisao/KISAO#KISAO_0000245"/>
                        <owl:someValuesFrom rdf:resource="http://www.biomodels.net/kisao/KISAO#KISAO_0000102"/>
                    </owl:Restriction>
                </owl:complementOf>
            </owl:Class>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://www.biomodels.net/kisao/KISAO#KISAO_0000245"/>
                <owl:someValuesFrom rdf:resource="http://www.biomodels.net/kisao/KISAO#KISAO_0000103"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://www.biomodels.net/kisao/KISAO#KISAO_0000245"/>
                <owl:someValuesFrom rdf:resource="http://www.biomodels.net/kisao/KISAO#KISAO_0000106"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://www.biomodels.net/kisao/KISAO#KISAO_0000245"/>
                <owl:someValuesFrom rdf:resource="http://www.biomodels.net/kisao/KISAO#KISAO_0000107"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://www.biomodels.net/kisao/KISAO#KISAO_0000245"/>
                <owl:someValuesFrom rdf:resource="http://www.biomodels.net/kisao/KISAO#KISAO_0000237"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <dc:created rdf:datatype="http://www.w3.org/2001/XMLSchema#date">2011-05-09</dc:created>
        <dc:creator xml:lang="en">AZ</dc:creator>
        <kisao:isOrganizational rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</kisao:isOrganizational>
        <oboInOwl:Namespace xml:lang="en">KISAO_DEPRECATED</oboInOwl:Namespace>
        <rdfs:label xml:lang="en">SUNDIALS method</rdfs:label>
        <rdfs:seeAlso rdf:datatype="http://www.w3.org/2001/XMLSchema#anyURI">http://identifiers.org/doi/10.1145/1089014.1089020</rdfs:seeAlso>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
        <skos:definition xml:lang="en">One of the methods, implemented in SUNDIALS (a suite of advanced computational codes for solving large-scale problems that can be modeled as a system of nonlinear algebraic equations, or as initial-value problems in ordinary differential or differential-algebraic equations).</skos:definition>
    </owl:Class>
    <owl:Axiom>
        <owl:annotatedSource rdf:resource="http://www.biomodels.net/kisao/KISAO#KISAO_0000284"/>
        <owl:annotatedProperty rdf:resource="http://www.w3.org/2000/01/rdf-schema#seeAlso"/>
        <owl:annotatedTarget rdf:datatype="http://www.w3.org/2001/XMLSchema#anyURI">http://identifiers.org/doi/10.1145/1089014.1089020</owl:annotatedTarget>
        <rdfs:comment xml:lang="en">Hindmarsh, A. C., et al., SUNDIALS: Suite of Nonlinear and Differential/Algebraic Equation Solvers, ACM Trans. Math. Softw., 31:363-396, 2005.</rdfs:comment>
    </owl:Axiom>
</rdf:RDF>



<!-- Generated by the OWL API (version 4.5.7.2018-12-02T02:23:35Z) https://github.com/owlcs/owlapi -->