KarrLab/wc_rules

from wc_rules.modeling.pattern import Pattern
from wc_rules.modeling.model import AggregateModel
from ..templates.graphs import *
from ..templates.rules import BindingModel

# Patterns
free_syk = Pattern(gSykTsh2,constraints = ['len(tsh2.bond)==0'])
free_gamma = Pattern(gReceptorGamma,constraints = ['gamma.ph==True','len(gamma.bond)==0'])
bound_syk = Pattern(gSykReceptor,constraints = ['gamma.ph==True'])

model = BindingModel(
    name = 'syk_receptor',
    reactants = {
        'rSyk':         free_syk,
        'rReceptor':     free_gamma,
        'rSykReceptor': bound_syk
        },
    targets = {
        'rSyk':         'tsh2',
        'rReceptor':     'gamma',
        'rSykReceptor': 'tsh2'
        }
)

data = {
    'association_constant':        6e-2, 
    'dissociation_constant':    20.0
}

model.verify(data)
model.defaults = data