KarrLab/wc_rules

from .templates import DephosphorylationModel
from .graphs import build_receptor, build_Syk, recruit_to_receptor, add_phosphosite_to_molecule

from wc_rules.modeling.pattern import Pattern
from wc_rules.modeling.model import AggregateModel

gRecPhospho = add_phosphosite_to_molecule(build_receptor([]),'receptor')
gFreeSykPhospho = add_phosphosite_to_molecule(build_Syk([]),'syk')
gMembraneSykPhospho = recruit_to_receptor(build_receptor(['gamma']), add_phosphosite_to_molecule(build_Syk(['tsh2']),'syk'))

model = AggregateModel(
    name = 'dephosphorylation',
    models = [ 
        DephosphorylationModel('receptor',gRecPhospho),
        DephosphorylationModel('membrane_syk',gMembraneSykPhospho),
        DephosphorylationModel('free_syk',gFreeSykPhospho),
        ]
    )

data = {
    'receptor':     {'dephosphorylation_rate': 20.0},
    'membrane_syk': {'dephosphorylation_rate': 20.0},
    'free_syk':        {'dephosphorylation_rate': 20.0}
}

model.verify(data)
model.defaults = data